The DHEA-s Blood Test, also known as the Dehydroepiandrosterone Sulfate test, is performed to assess adrenal gland function. It measures DHEA-s, a steroid hormone that is produced by the adrenal gland, and serves as a building block for the male sex hormone testosterone and the female sex hormone estrogen. This test is helpful in assessing adrenal tumors or cancers, determining the cause of masculinization among females, and identifying the cause of early puberty in boys.